Polynucleotides

Polynucleotides are an advanced injectable treatment designed to repair, regenerate, and improve the overall quality of the skin at a cellular level.

Duration: 15-30 min
Results: Visible improvement from 1-4 weeks
Downtime: Some redness and bumps at the injection site for 12-24 hours
Longevity: 4-6 months typically

What are Polynucleotides?

Polynucleotides are an advanced injectable treatment designed to repair, regenerate, and improve the overall quality of the skin at a cellular level.

Derived from purified DNA fragments, polynucleotides work by stimulating the skin’s natural repair processes, improving tissue regeneration, and enhancing hydration. They are particularly known for their ability to improve skin health, rather than simply adding volume or temporarily smoothing lines.

How do Polynucleotides work?

Polynucleotides are injected into targeted areas of the skin, where they begin to stimulate fibroblast activity, these are the cells responsible for producing collagen and elastin.

This process helps to:

  • Repair and regenerate damaged skin
  • Improve skin elasticity and firmness
  • Increase hydration from within
  • Strengthen the skin barrier
  • Reduce inflammation and support healing

Over time, this leads to healthier, stronger, and more resilient skin.

What makes Polynucleotides different?

Polynucleotides are often referred to as a regenerative treatment, focusing on long-term skin health rather than immediate cosmetic change.
Stimulate true skin regeneration at a cellular level
Improve skin quality, not just appearance
Anti-inflammatory and healing properties
Ideal for delicate or compromised skin
Natural, progressive results

Who is it suitable for?

Polynucleotides are particularly beneficial for:
Thin, fragile, or ageing skin
Under-eye rejuvenation (dark circles, crepey skin)
Acne scarring or damaged skin
Rosacea-prone or sensitive skin
Loss of elasticity and early signs of ageing

They are suitable for patients looking for a more regenerative, skin-health-focused approach to aesthetics.

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What results can you expect?

Results develop gradually as the skin repairs and regenerates itself. Patients often notice improvements in hydration, texture, and skin strength within a few weeks, with continued improvement over time.

A course of 3 treatments is usually recommended for optimal results, followed by maintenance sessions every 4-6 months to support ongoing skin health.

Prices

1 Treatment

£200

3 Treatments

£525

Aftercare Advice

Keep the skin hydrated and protected with SPF
Follow all personalised advice given during your consultation
Small lumps or bumps may be visible at injection sites and can last 24–72 hours
Avoid touching or rubbing the treated area for 24 hours
Avoid makeup for at least 12–24 hours
Avoid exercise, alcohol, and heat exposure for 24
Avoid active skincare (retinol, acids, exfoliants) for 3–5 days
Avoid facials or other treatments for 1-2 weeks

Frequently Asked Questions

What are polynucleotides made from?

Polynucleotides are derived from highly purified DNA fragments. They are carefully processed to be safe and biocompatible, working in harmony with your body to support natural skin regeneration.

How many treatments will I need?

A course of 2–3 treatments, spaced a few weeks apart, is typically recommended for optimal results. Your treatment plan will be tailored during your consultation.

When will I see results?

Results develop gradually as the skin repairs and regenerates. You may notice improvements in hydration and texture within a few weeks, with continued enhancement over time.

How long do results last?

Results can last several months, particularly when a full course of treatment is completed. Maintenance sessions are recommended to sustain long-term skin health.

Are polynucleotides safe?

Yes, when performed by a qualified medical professional. Polynucleotides are biocompatible and well-tolerated, and we follow strict clinical protocols to ensure your safety at all times.

Is there any downtime?

Downtime is minimal. You may experience mild swelling, redness, or small bumps at the injection sites, which usually settle within 24–48 hours.

Can polynucleotides be used under the eyes?

Yes, they are particularly effective for the delicate under-eye area, helping to improve skin quality, hydration, and crepey texture.

Will I look natural?

Yes. Polynucleotides work to improve the health and quality of your skin from within, resulting in subtle, natural-looking rejuvenation rather than any change in facial structure.

Can I have polynucleotides if I have a fish allergy?

Polynucleotides are typically derived from fish (usually salmon or trout), so they may not be suitable for individuals with a fish allergy. If you have a known allergy, it’s important to let us know during your consultation so we can assess your suitability and discuss alternative treatment options.